Monitoring of Salmonellae in Kyrgyzstan
Epizootiological, Epidemiological and Ecological Assessment of Salmonellosis in Kyrgyzstan
Tech Area / Field
- AGR-DIS/Disease Surveillance/Agriculture
- ENV-EHS/Environmental Health and Safety/Environment
- MED-DIS/Disease Surveillance/Medicine
3 Approved without Funding
Kyrgyz Agrarian University, Kyrgyzstan, Bishkek
- Kyrgyz Research Institute of Livestock, Veterinary and Pastures, Kyrgyzstan, Bishkek\nNational Academy of Sciences of Kyrgyzstan / Biotechnology Institution, Kyrgyzstan, Bishkek
- Purdue University / Animal Disease Diagnostic Laboratory, USA, IN, West Lafayette
Project summarySalmonellosis is an infectious disease of humans, animals and birds (zooanthroponosis) caused by the agent belonging to Genus Salmonella of Enterobacteriacea Family with fecal-oral infection mechanism, which is characterized by a combination of intoxication and dyspeptic syndromes, a possible development of dehydration and is one of the most difficult and by far the most unsolved problems of public health and veterinary medicine. The disease is included in the list A (especially dangerous diseases of animals) by the International Epizootiology Bureau (IEB).
All over the world there is a stable rising tendency of the incidence of salmonellosis, its proportion among reported cases of enteric diseases in UK, USA, Germany, Switzerland and other countries ranges 35 - 90%. The Kyrgyz Republic has had a steadily bad epidemic situation regarding salmonellosis for the last 10-15 years. According to our data (K.Abdykerimov, 1998, 2006; A.Z.Tulobaev, 1999) in animals, birds bacterial gastrointestinal diseases make up 31,6 - 60,8% of all infectious diseases.
Many factors contribute to a wide distribution of salmonellosis diseases.
Ill persons and salmonella carriers also can be a source of infection.
The main mechanism of infection is alimentary (enteral), the leading salmonella transmission routes are food-, water-borne and person to person contact. The main salmonella transmission factors in food-related outbreaks are meat and meat products (46,2%), jellied meat (28,0%), eggs (14,0), less common are confectionary, milk, vegetables, fruits, berries, fish and other exo- or endogenously infected food products. Water can be a factor of salmonellas transmission when used in food processing units (K.S.Omurzakova et al., 1994).
Salmonellosis has a summer-autumn seasonality.
The salmonellosis pathogen is stable in the environment, thermolabile, able to propagate in different food products.
Despite the existing body of scientific data on salmonellosis, comprehensive studies on the epizootological, epidemiological and ecological assessment of factors and pathways of the infection spread have not been conducted in the Kyrgyz Republic.
In view of the foregoing, the aim of the project is to carry out epizootiological, epidemiological and ecological biomonitoring of factors and pathways of the spread of salmonellae in the Chui and Issyk-Kul oblasts of the Kyrgyz Republic, which will enable establishing a true epizooto- and epidemiological picture of salmonellosis in our country, obtaining cultural isolations of salmonellas for the study of their morphological, cultural, serological properties, and choosing strains for vaccine development.
The world’s research tendency regarding the diagnosis and vaccine prevention of salmonellosis will be studied.
The project will be performed mainly by weapons scientists and specialists from the Kyrgyz Republic who work in the field of the salmonellosis epizootology, epidemiology, microbiology and prevention in animals, birds and humans. The project will reorient weapons scientists and specialists to peaceful activity, i.e. development of technologies for protection of the environment, humans and birds, and studies addressing biosafety problems.
This meets the objective of ISTC “to provide possibilities for weapons scientists and experts to conduct research with peaceful aims”.