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Centrifugal Extractors for Drug Production (R)

#0344


Centrifugal Extractors for Processing Medicines.

Tech Area / Field

  • BIO-IND/Industrial Biotechnology/Biotechnology
  • BIO-MIB/Microbiology/Biotechnology
  • BIO-CHM/Biochemistry/Biotechnology
  • MED-DRG/Drug Discovery/Medicine

Status
8 Project completed

Registration date
05.01.1995

Completion date
05.04.2000

Senior Project Manager
Kondratenkov Yu B

Leading Institute
NIKIMT (Institute of Assembly Technology), Russia, Moscow

Collaborators

  • Idaho National Engineering and Environmental Laboratory, USA, ID, Idaho Falls

Project summary

The project task is the development of centrifugal extractors for processing medicines. The performance of the project makes it possible:

- to provide an alternative occupation for the part of scientists and engineers of the Institute participating in the development of industrial technology for the weapon-grade uranium and plutonium on the basis of centrifugal extractors with nuclear safe geometry and remote maintenance by robots and manipulators;

- to solve problems inherent in the extraction of antibiotics and medicines from plants: necessity for a short residence of solutions in the apparatus, difficulty in ovecoming the system's tendency to emulsify and especially presence of solid impurities in the process ed solutions.

These specific features require the extended hydrodynamic and mass transfer studies for designing the centrifugal extractors and modelling the extraction processes when processing solutions contain solid admixtures. As a result new apparatus having simple and reliable designs are to be developed which will increase the production of medicines needed badly in Russia.

Since preparation of medicines is a large-capacity production one will have to increase the dimensiones of the main units a few tens of times when designing the medical centrifugal extractor. In this connection the apparatus becomes nuclear hazardous as to volume and dimensions as the critical mass of the nuclear fuel that is in the extractor at one moment is bound to be exceeded.

It is very important that when designing the medical centrifugal extractor the geometrical similarity of all its elements to those of the apparatus for the production of weapon-grade uranium and plutonium will be purposefully avoided. So the reverse attempt to design an apparatus for military purposes will require many years of research because the medical centrifugal extractor proposed in this project cannot be used as a prototype.


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