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Models for Identification of the Flu Virus

#G-1946


An estimation of the Level of Biological Security and Management of Biological Risks under Uncertainty

Tech Area / Field

  • BIO-INF/Bioinformatics/Biotechnology

Status
3 Approved without Funding

Registration date
12.05.2011

Leading Institute
Georgian Technical University, Georgia, Tbilisi

Collaborators

  • Wroclaw University of Environmental and Life Sciences / The Faculty of Environmental Engineering and Geodesy, Wroclaw\nValley Cancer Institute, USA, CA, Los-Angeles\nIB Hochschule Berlin, Germany, Stuttgart\nBulgarian Defence Industry Association, Bulgaria, Sofia

Project summary

Biosafety is a set of measures intended for elimination of potential dangerous results of usage of the methods and products of biotechnologies. In setting of the goals of the Protocol on Biosafety (The Cartagena Protocol on Biosafety The Cartagena Protocol on Biosafety to the Convention on Biological Diversity is an international treaty governing the movements of living modified organisms (LMOs) resulting from modern biotechnology from one country to another. It was adopted on 29 January 2000 as a supplementary agreement to the Convention on Biological Diversity and entered into force on 11 September 2003. http://bch.cbd.int/protocol/background/ ) the principle of taking precautionary measures was taken as a basis. According to this principle, GMO and the products of their processing are deemed to be potentially dangerous, until their safety is not evidenced by all methods specified in the relevant normative documents.

The goal of the research is to design biosafety computer models under uncertain conditions for the purposes of identification and biological detecting of the flu virus and management of biological risks of virulence of the infectious agent (three serotypes of viruses, groups A, B and C) on the basis of modelling, in the situation where information and data for decision-making are of incomplete and fuzzy nature.

Main staff of the project is fourteen highly qualified specialists in the following areas – biology, chemistry, medicine, mathematics and programming, out of which 11 are Doctors and 3 - masters. In relation of the project theme they have publications of research works and monographs both in Georgian and international magazines, including impact factor magazines.

Expected results could be formulated in a form of scenario for evaluation of biosafety, management of bio-risks, taking into consideration the short-, average- and long-term prospects. Within the project, for organization and operation of the computer system for evaluation of biosafety and bio-risks management the software will be developed, with further verification; by means of the latter the interface is developed for evaluation of biosafety and bio-risks management.

Georgian technical university plans to sell the part of its rights – in a form of license on the developed methodologies.

Project implementers permanently study all possible sources for seeking of the new contacts and expansion of already existing ones. For this purpose the representatives of implementers systematically attend all seminars, meetings and congresses in this area.

As the project employes the professionals aware in the sphere of mass destruction weapons and the project is exclusively of peaceful nature, it fully complies with the ISTC goals. Compliance with these goals would be achieved through wide involvement of the scientists from the participating organizations in the peaceful scientific community trough providing information about project at the international seminars and conferences.

Project duration 30 months, number of participants -14, budget - US$ 202000.

The employees of IB Hochschule Berlin and Bulgarian Defence Industry Association expressed their desire to be collaborators for this project. According to the letters of Prof. Uli Rothfuss and Corresponding Member of Bulgarian Academy of Scieces, D.S.C. Stefan Vodenicharov, their groups are ready to exchange information with us, take part in joint meetings and, probably, conferences or workshops to intensify our relations.

Key novelty in implementation of work will be application of the fuzzy sets for analysis and evaluation of the biosafety level and bio-risks management, no similar application of the fuzzy logic has taken place earlier, to our best knowledge

Analysis and application of the managerial decisions in the conditions of ambiguity is very valuable methodology in case of complicated, ambiguous data, or their lack for decision-making, at any level, in any sphere, especially in the sphere of biosafety and bio-risks management.


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